Temporary Scientist I, Computational Chemistry

Temporary Scientist I, Computational Chemistry

W2 Contract

Pay Rate: $55 - $65 per hour

Location: Redwood City, CA - Onsite Role

Job Summary:

We are seeking a motivated Computational Chemist to join our dynamic team. This position offers an exciting opportunity to drive drug discovery through cutting-edge computational methods, working at the intersection of structural biology, medicinal chemistry, biology, and data science to accelerate the development of transformative therapeutics for patients.

Duties and Responsibilities:
• Determine, propose, and implement ML methodologies, analyze large data, and document research to identify clustering methods for Macrocycles.
• Ability to work with software packages/GitHub repositories, test, and use them.
• Design and implement virtual screening workflows leveraging both structure-based and ligand-based computational methods to discover novel hit compounds and accelerate lead optimization processes.
• Partner with multidisciplinary, collaborative teams in Discovery Sciences to help analyze structure-activity relationships (SAR) and make data-driven decisions by following existing SAR trends to design strategies for Ro5 and bRo5 molecules.
• Devise and execute strategies to augment our hit-finding abilities by designing diverse chemical libraries.

Requirements and Qualifications:
• Ph.D. in computational chemistry or related field.
• Understanding of contemporary computational chemistry methods and their use in protein-ligand analysis and drug design, such as docking, virtual screening, pharmacophore modeling, MD simulation, QM calculations, etc.
• Experience with computational chemistry, cheminformatics, data science, and machine learning software.
• Scientific programming or scripting in Bash, Python, R, Java, C, or similar languages.
• Excellent oral and written communication skills. Experience in positively influencing team decisions and effectively collaborating across multidisciplinary environments.
• Driven by a desire to be innovative and creative in a high-energy, fast-paced environment.

Desired Skills and Experience

Computational Chemistry, Cheminformatics, Machine Learning, Data Science, Structural Biology, Medicinal Chemistry, Drug Discovery, Large-Scale Data Analysis, Clustering Methodologies, Macrocycles, Protein-Ligand Analysis, Molecular Docking, Virtual Screening, Structure-Based Drug Design, Ligand-Based Drug Design, Pharmacophore Modeling, Molecular Dynamics Simulation, Quantum Mechanics Calculations, Structure-Activity Relationships, Lead Optimization, Hit Discovery, Chemical Library Design, Ro5 Molecules, bRo5 Molecules, Scientific Programming, Bash, Python, R, Java, C, GitHub, Software Package Testing, Research Documentation, Data-Driven Decision-Making, Multidisciplinary Collaboration, Scientific Communication, Innovation

Bayside Solutions, Inc. is not able to sponsor any candidates at this time. Additionally, candidates for this position must qualify as a W2 candidate.

Bayside Solutions, Inc. may collect your personal information during the position application process. Please reference Bayside Solutions, Inc.'s CCPA Privacy Policy at www.baysidesolutions.com.