Technical SETA - Computational Biophysics (TS/SCI #26-117)

Strategic Analysis, Inc. is seeking a skilled Technical SETA - Computational Biophysicist to support the Biological Technologies Office (BTO) at the Defense Advanced Research Projects Agency (DARPA).
Summary: Provides critical subject matter expertise and programmatic support to DARPA BTO Program Managers, translating foundational and mid-level biophysical principles and applied modeling experience into technical oversight, proposal evaluation, performer assessment and management for cutting-edge structural biology and biotechnology programs.

Responsibilities:
- Evaluates performer-designed molecular dynamics (MD) simulations, custom analytical pipelines, and scripts (Python, C++, Bash) to ensure they meet structural bioinformatics and free energy calculation standards.
- Reviews complex methodologies for merging computational models with empirical biological data (e.g., cryo-EM, X-ray crystallography) utilizing deep conceptual knowledge of tools like GROMACS, AMBER, NAMD, and PyMOL.
- Translates domain subject matter expertise into actionable support for DARPA BTO Program Managers by tracking performer milestones, maintaining program data logs, and drafting technical content for briefings, transition reports, and new BAAs.

Degree: Engineering, Science, Business, Program Management, Operations, Public Policy, or a related field.
PMP Certification is required.
Clearance: TS/SCI required

Work Location: Full time onsite at Arlington VA headquarters, DARPA.

PI286288565