Senior Director, Oncology Reverse Translation

Lead oncology reverse-translation research at Johnson & Johnson, connecting clinical observations with disease biology, therapeutic resistance, discovery, and pipeline strategy. Direct laboratory programs and scientific teams across solid and hematologic cancers.
• नौकरी का शीर्षक: Senior Director, Oncology Reverse Translation
• कंपनी: Johnson & Johnson
• स्थान: संयुक्त राज्य, कैलिफ़ोर्निया, मैसाचुसेट्स, न्यू जर्सी, पेंसिल्वेनिया
• कार्यस्थल का प्रकार: हाइब्रिड
• रोजगार का प्रकार: पूर्णकालिक, 40 hours per week
• $1,96,000 – $3,42,700 / वर्ष
• अनुभव: वरिष्ठ
• डिग्री आवश्यक: हाँ
• अनुवादक
• आवश्यक भाषा: अंग्रेज़ी
• उद्योग: औषधियाँ, स्वास्थ्य बीमा, स्वास्थ्य सेवा
• H1B वीज़ा प्रायोजक

विवरण
• Lead independent studies addressing high-priority mechanistic questions across oncology
• Set priorities across disease-focused, cross-MOA, MOA-focused, cross-disease, and shelved-program research
• Translate findings into next-generation hypotheses and combination strategies that support Discovery pipeline growth
• Address active mechanistic questions raised by translational research leads across solid and hematologic indications
• Direct laboratory research into program efficacy, failure, and resistance development
• Design and evaluate combination approaches to increase treatment benefit and counter resistance
• Establish and operate the laboratory while bringing disease-area scientists together under unified leadership
• Oversee omics, functional and perturbation biology, in vitro and in vivo studies, and organoid platforms
• Participate in the Core Senior Leadership Team for Translational Research and help shape organization-wide scientific strategy
• Act as the scientific connection between reverse translation and Discovery
• Partner with Medical Affairs and Commercial on lifecycle and portfolio priorities
• Lead mechanism-focused translational research publications, including the Mechanism Series
• Mentor scientists and foster rigorous, open scientific debate
• Evaluate team performance by its influence on program and portfolio decisions

आवश्यकताएँ
• Doctorate in cancer biology, molecular biology, immunology, pharmacology, or a related discipline, such as a PhD, MD, or MD/PhD
• At least 10 years of experience for Senior Director consideration or 12 years for Executive Director consideration in oncology discovery or translational research, including direct laboratory leadership
• Broad expertise in mechanisms and mechanisms of resistance, with demonstrated success converting clinical observations into testable laboratory hypotheses
• Experience building and managing wet-lab teams and operating omics and functional-characterization platforms
• Ability to work effectively at the Discovery–Translational Research interface within a matrix spanning multiple disease areas
• Strong publication history, including first- or last-author papers, combined with clear scientific communication
• Preferred: expertise in multiomics, perturbation biology, organoid models, and computational data integration
• Preferred: experience extracting portfolio-relevant insights from shelved programs
• Preferred: record of developing combination and resistance-reversal strategies across modalities
• Preferred: experience collaborating with Medical Affairs and Commercial on lifecycle-focused science

लाभ
• Pension retirement plan
• 401(k) savings plan
• Long-term incentive program
• 120 hours of vacation per calendar year
• 40 hours of sick time per calendar year, with 48 hours for Colorado employees and 56 hours for Washington employees
• 13 paid holidays, including floating holidays, per calendar year
• Up to 40 hours of work, personal, and family time per calendar year
• 480 hours of parental leave within one year of a child's birth, adoption, or placement in foster care
• Bereavement leave of 240 hours for an immediate family member or 40 hours for an extended family member per calendar year
• 80 hours of caregiver leave during a rolling 52-week period
• 32 hours of volunteer leave per calendar year
• 80 hours of military spouse time off per calendar year
• Inclusive interviews and support for workplace accommodations