About the Role Our client, a leading global Contract Research Organization (CRO), is seeking a highly experienced Senior Clinical Research Associate (CRA) to manage and oversee complex oncology clinical trials. This vital role requires an on-site presence in **Philadelphia, Pennsylvania, US**, to ensure the highest standards of data integrity and patient safety. You will be responsible for monitoring clinical trial sites, ensuring adherence to protocols, Good Clinical Practice (GCP), and regulatory requirements. The ideal candidate possesses a deep understanding of oncology drug development and extensive site management experience. This is an exceptional opportunity to contribute to cutting-edge research that is shaping the future of cancer treatment and to advance your career within a supportive and growth-oriented organization. Your dedication to meticulous site management will be key to the success of these critical trials in **Philadelphia, Pennsylvania, US**.

Key Responsibilities Conduct pre-study, initiation, interim, and close-out visits for clinical trial sites. Ensure sites are adequately trained on the protocol, study procedures, and regulatory requirements. Monitor clinical trial data for accuracy, completeness, and compliance with protocol and GCP. Identify, document, and resolve site-level issues and deviations in a timely manner. Serve as the primary point of contact for assigned clinical sites. Manage site performance and identify opportunities for improvement. Ensure timely drug supply management and investigational product accountability at sites. Prepare and present site monitoring reports to study teams and management. Participate in the development of site monitoring plans and essential study documents. Foster strong relationships with investigators, site staff, and study sponsors. Requirements Bachelor's degree in a life science, nursing, or related field. Advanced degree is a plus. Minimum of 5 years of experience as a Clinical Research Associate, with significant experience in oncology trials. In-depth knowledge of ICH-GCP guidelines and relevant regulatory requirements (FDA, EMA). Proven experience in monitoring multiple clinical trial sites and managing study timelines. Excellent understanding of clinical trial processes, including drug development, regulatory submissions, and site operations. Strong analytical, problem-solving, and decision-making skills. Exceptional organizational and time management abilities. Outstanding interpersonal and communication skills, with the ability to build rapport and influence stakeholders. Proficiency in clinical trial management systems (CTMS) and electronic data capture (EDC) systems. Ability to travel as required for site monitoring and company meetings. Benefits Our client offers a competitive salary, performance incentives, and a comprehensive benefits package including health, dental, and vision insurance, a 401(k) retirement plan, paid time off, and continuous professional development opportunities. This on-site position is based in **Philadelphia, Pennsylvania, US**, providing a stable and collaborative work environment.