Senior Clinical Project Manager, Oncology

Piper Companies is seeking a Senior Clinical Project Manager, Oncology to join a leading Clinical Research Organization supporting cutting-edge oncology studies for a fully remote permanent position. The Senior Clinical Project Manager, Oncology will oversee the planning, execution, and delivery of complex cancer clinical trials, ensuring studies are conducted efficiently, meet regulatory standards, and achieve key project objectives across domestic and global research sites.
Responsibilities of the Senior Clinical Project Manager, Oncology:
Direct all phases of oncology clinical studies, including study start-up, enrollment, execution, and closeout activities while maintaining project timelines and budgets.
Collaborate with internal departments, study vendors, investigative sites, and sponsors to ensure successful trial delivery and achievement of project milestones.
Oversee site activation, enrollment performance, patient retention efforts, and operational challenges across multiple oncology programs.
Identify and address project risks, monitor financial forecasts, manage scope adjustments, and provide regular status updates to stakeholders.
Ensure compliance with protocol requirements, GCP standards, regulatory guidelines, safety reporting processes, and inspection readiness activities.
Qualifications for the Senior Clinical Project Manager, Oncology:
Bachelor's degree in Life Sciences, Nursing, Pharmacy, or a related scientific discipline.
5+ years of clinical research experience with at least 2 years of clinical project management experience within a CRO, biotechnology, or pharmaceutical setting.
Previous experience managing oncology clinical trials, including solid tumor and/or hematology studies across Phase I-IV research.
Strong understanding of ICH-GCP guidelines, global regulatory requirements, study budgeting, forecasting, and vendor management.
Experience working with CTMS, EDC systems, eTMF platforms, and other clinical trial technologies.
Excellent leadership, communication, organizational, and stakeholder management skills with the ability to oversee global or multi-site clinical programs.
Compensation for the Senior Clinical Project Manager, Oncology:
Salary Range: $170,000-$200,000/year (USD)
Comprehensive Benefits: Medical, Dental, Vision, sick leave if required by law, 401(k), paid time off, and additional employee wellness programs.
This job opens for applications on 11/13/26. Applications for this job will be accepted for at least 30 days from the posting date.
Keywords: oncology, hematology, solid tumors, immuno-oncology, clinical research, clinical trials, CRO, project management, clinical operations, study start-up, patient enrollment, site activation, vendor management, CTMS, EDC, eTMF, ICH-GCP, regulatory compliance, pharmacovigilance, data management, risk management, forecasting, study budgeting, audit readiness, inspection readiness, clinical development, biotechnology, pharmaceutical, global trials, oncology therapeutics, investigational product, clinical study oversight, oncology drug development, sponsor management, cross-functional leadership.