### **Overview**

Seeking a Scientist to join the Oncology & Immuno-Oncology Department. The team is developing novel therapeutic modalities to activate the immune system and eradicate tumor cells. You will be responsible for designing and carrying out in vitro and in vivo experiments leading to cancer immunology target validation and development of therapeutic antibodies.

**Responsibilities**
- Performing tumor implantations and measuring tumors to validate targets and evaluate lead molecules in different mouse tumor models
-
- Performing injections through various routes (IP, IV, Sub-Q)
- Bleeding mice and isolating mouse tissues
- Isolating immune cells from mouse and human tissues for further functional and phenotypic characterization
- Performing ex-vivo immunophenotyping using multicolor flow cytometer and analyzing flow cytometry data
- Executing and analyzing molecular biology assays such as ELISA/MSD, immunoblotting, RT-PCR etc.
- Maintaining and culturing cells as necessary
- Developing new methods or technologies, troubleshooting experiments
- Writing protocols and study reports, producing and maintaining accurate electronic records
- Analyzing data using FlowJo, Microsoft Excel and GraphPad Prism
- Communicating findings to peers and management

- **Requirements**BS or MS degree in Cell biology, Molecular biology, Biochemistry, Immunology or related fields
-
- 4-5+ Experience working in an immunology or cancer biology laboratory.
- Experience conducting experiments using mouse models with training in proper handling and care of mice is preferred.
- A general knowledge of immunology and immune-oncology field as well as experience in tissue culture and cell-based assays and flow cytometry is a plus.