Scientist

Job Description





- Seeking a highly motivated research scientist to join a dynamic team supporting biologics drug discovery and engineering.
- Responsible for the design and execution of in vitro display technologies for lead antibody identification, optimization, and will collaborate with other team members to generate stage-gate appropriate in vitro and in vivo data packages supporting proof-of-concept (PoC).
- This role leverages scientific expertise to develop and implement research supporting the discovery, optimization, and mechanistic understanding of the molecular pharmacology of therapeutic molecules across Therapeutic Areas.
- Able to analyze, document, and report data effectively, and possess excellent communication skills with comfort presenting in group settings.





Qualifications





- BS or MS in Biology or a related field with typically 5+ years of experience (BS) OR 2+ years of experience (MS) in a pharmaceutical and/or relevant research environment
- Experience in antibody engineering and optimization (e.g., affinity modulation, liability engineering, humanization)
- Experience with antibody library design and construction
- Experience in mammalian cell culture and multiplex flow cytometry
- Experience with automation of biologics discovery processes
- Proficiency with Prism, Geneious and/or Genedata
- Excellent oral and written communication skills, including proficiency with MS Office Suite (Excel, PowerPoint, Word)
- Hands-on experience with in vitro antibody discovery display technologies (e.g., phage display, yeast display)
- Direct experience with binding assays (e.g., ELISA, flow cytometry or SPR)
- Strong molecular and cell biology skills (e.g., molecular cloning, sequence analysis, E coli and/or yeast culture, mammalian cell culture, etc.)
- Familiarity with protein structure, affinity, antibodies and antibody fragments
- Experience with GraphPad Prism for data analysis and visualization
- Expertise in ELISA, FACS
- Strong experience with display technologies, particularly yeast display and phage display.
- Experience developing and optimizing antibody discovery or engineering workflows.
- SPR experience preferred.
- Hands-on experience with in vitro antibody discovery and engineering, preferably 3-5+ years.





California Fair Chance Act



Synectics Inc. will consider qualified applicants with a criminal history pursuant to the California Fair Chance Act. You do not need to disclose your criminal history or participate in a background check until a conditional job offer is made to you. After making a conditional offer and running a background check, if Synectics Inc. is concerned about conviction that is directly related to the job, you will be given the chance to explain the circumstances surrounding the conviction, provide mitigating evidence, or challenge the accuracy of the background report. Find out more about the Fair Chance Act by visiting calcivilrights.ca.gov/fair-chance-act/.



Benefits



Healthcare Insurance: Synectics offers eligible employees and their dependents healthcare coverage through BlueCross BlueShield of Illinois. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics. Premiums are subsidized by Synectics.



Dental Insurance: Synectics offers eligible employees and their dependents a dental plan through MetLife. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.



Vision Insurance: Synectics offers eligible employees vision insurance through VSP. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.



401(k) Plan: The Synectics Inc. Investment Savings Retirement Plan. Synectics offers all employees who are 21 years of age or older the opportunity to invest in the 401(k) Plan on the first of the month following at least 1 calendar year after employment begins.



Synectics is an equal opportunity employer.