Research Associate – Gene Therapy Analytical Development 3663083

Be Part Of A High-Performing Team

Join a science-driven biopharmaceutical organization focused on developing innovative therapies for patients with serious and rare diseases. This opportunity sits within a Gene Therapy Analytical Development group responsible for building reliable analytical methods that support advancing gene therapy programs through development. The environment is highly collaborative and hands-on, bringing together analytical development, quality, bioinformatics, and regulatory expertise to solve complex scientific challenges.

What's In Store For You


- Engagement: W2 only (no C2C/1099)
- Gain hands-on experience supporting analytical method development for gene therapy programs.
- Work closely with experienced scientists while developing deeper expertise in molecular biology and viral vector analytics.
- Collaborate with cross-functional partners across QC, Bioinformatics, and Regulatory CMC.
- Contribute to assays that directly support the characterization and development of advanced therapeutics.


How You Will Make An Impact


- Develop, execute, and optimize viral genome titer assays using ddPCR and qPCR technologies.
- Design and evaluate primers and probes for specificity, sensitivity, precision, and reproducibility.
- Optimize PCR assay conditions, including cycling parameters, template concentrations, and inhibitor-related variables.
- Perform DNA and RNA extraction, purification, quantification, and sample preparation across multiple sample types.
- Apply restriction enzyme digestion and other molecular biology techniques to support assay development.
- Troubleshoot assay performance issues and conduct structured investigations into inconsistent or unexpected results.
- Analyze experimental data and maintain accurate technical reports, laboratory notebooks, and supporting documentation.
- Maintain laboratory records consistent with applicable GMP/GLP documentation practices.
- Partner with analytical development, quality, bioinformatics, and regulatory colleagues to advance gene therapy programs.
- Stay current with developments in ddPCR, molecular analytics, NGS, and gene therapy technologies.


Are You an Experienced Molecular Biology Research Associate Ready to Make an Impact?


- B.S. or M.S. in Molecular Biology, Biochemistry, Biotechnology, or a closely related life sciences discipline.
- Hands-on laboratory experience with qPCR and/or ddPCR, including assay setup, data interpretation, optimization, and troubleshooting.
- Experience designing and evaluating PCR primers and probes.
- Strong experience with DNA and RNA purification and quantification.
- Familiarity with restriction enzyme digestion and standard molecular biology or cloning techniques.
- Strong attention to detail with the ability to produce accurate, complete laboratory documentation.
- Ability to work effectively in a fast-paced laboratory environment while receiving scientific direction from senior team members.
- Strong written, verbal, analytical, and collaborative communication skills.
- Direct experience with Bio-Rad QX200, QXOne, or another ddPCR platform is highly desirable.
- Exposure to AAV or other viral vectors, analytical method development, GMP/GLP laboratories, NGS workflows, or JMP/statistical analysis is preferred.






Skills:

Analysis Skills, Analytical Development, Analytical Method Development, Assay Development, Assays, Biochemistry, Bioinformatics, Biology, Biotech and Pharmaceutical, Channel Strategies, Cloning, Communication Skills, Cross-Functional, DNA, Data Analysis, Detail Oriented, Disease, Documentation, Droplet Digital PCR (ddPCR), GLP (Good Laboratory Practices), GMP (Good Manufacturing Practices), Gene Therapy, Genomics, Identify Issues, Laboratory, Laboratory Notebook, Molecular Analysis, Molecular Biology, Next Generation Sequencing (NGS), Polymerase Chain Reaction (PCR), Presentation/Verbal Skills, Quality Control, Real-time PCR (qPCR), Regulations, Statistics, Team Player, Writing Skills



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