Principal Investigator
Pharmaron · Baltimore, MD
FULL-TIME
Posted Oct 31, 2026
Job Description
Position: Principal Investigator
Salary Range: $200 - $285k (DOE)
Location: Baltimore, MD (On-site)
About Pharmaron
Pharmaron is a global contract research and manufacturing organization (CRO/CDMO) helping pharma and biotech companies bring new therapies to life. With over 25,000 employees worldwide across 28 locations in the US, UK, China, and Singapore, we support drug discovery through to manufacturing with fully integrated high-quality services.
We're proud of the impact we make and just last year, we supported 887 discovery projects, 1,100+ CMC programs, and 1,397 clinical trials across all phases. Our teams are involved in everything from small molecules, ADC's, biologics, and gene therapies and we work with more than 3,300 global customers. To learn more, visit www.pharmaron.com.
What You'll Do
Pharmaron is seeking an experienced physician to serve as a Principal Investigator within our growing Phase I Clinical Research Unit in Baltimore, Maryland.
This is a unique opportunity for a board-certified physician who is passionate about advancing medicine through clinical research while maintaining a strong focus on participant safety and quality care. Clinical research experience is welcomed but not required. Physicians with backgrounds in Internal Medicine, Family Medicine, Emergency Medicine, or related specialties are encouraged to apply.
As Principal Investigator, you will provide medical leadership for early-phase clinical studies, oversee participant safety, collaborate with sponsors and scientific teams, and help shape the future growth of our clinical research programs.
Key Responsibilities:
Clinical Leadership
Serve as Principal Investigator or Sub-Investigator for Phase I-III clinical studies
Provide medical oversight and ensure participant safety throughout study conduct
Review eligibility, medical histories, adverse events, and safety data
Conduct physical examinations and medical assessments as required
Study Execution & Scientific Collaboration
Partner with sponsors and internal teams on protocol review, study design, and implementation
Support dosing activities and ongoing medical monitoring
Contribute to study interpretation, reporting, and regulatory submissions
Provide scientific and medical consultation to project teams and clients
Regulatory & Quality Oversight
Ensure studies are conducted in compliance with ICH-GCP, FDA regulations, and applicable guidelines
Maintain protocol integrity and oversight responsibilities as listed on FDA Form 1572
Support inspections, audits, and regulatory interactions when required
Team Leadership
Mentor and guide Clinical Research Coordinators, nurses, and study staff
Promote a culture of participant safety, quality, and operational excellence
Collaborate closely with Medical, Clinical Operations, Pharmacy, Laboratory, and Business Development teams
What We're Looking For:
Required Qualifications
MD or DO degree from an accredited medical school
Board Certification in a recognized specialty
Active and unrestricted medical license
Minimum 5 years of clinical practice experience
Current CPR and ACLS certifications
Strong understanding of patient care, medical ethics, and clinical decision-making
Excellent communication and leadership skills
Preferred Qualifications
Previous clinical research experience as a Principal Investigator, Sub-Investigator, or treating physician
Experience supporting Phase I or early clinical development programs
Familiarity with ICH-GCP, FDA regulations, and clinical trial operations
DEA registration
Background in Internal Medicine, Family Medicine, or Emergency Medicine
Why Pharmaron?
Pharmaron is a premier service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities and established a broad spectrum of research, development, and manufacturing service capabilities throughout the entire drug discovery, preclinical, and clinical development process across multiple therapeutic modalities, including small molecules, biologics, and CGT products. With over 25,000 employees and operations in the US, UK, China, and Singapore. Pharmaron has an excellent track record in delivering R&D solutions to its partners in North America, Europe, Japan, and China.
Collaborative Culture: You will thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values at Pharmaron. Our culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners, and collaborators.
Benefits: As part of our commitment to your well-being, we offer a comprehensive benefits package:
Comprehensive Medical, Dental & Vision Insurance with significant employer contributions
401(k) Retirement Plan with generous employer matching
Generous Paid Time Off (PTO), Paid Sick Leave & Company Holidays to support work-life balance
Employer-funded Health Savings Account (HSA) contributions (for eligible plans), plus Healthcare & Dependent Care Flexible Spending Accounts
100% Employer-paid Employee Life Insurance, AD&D, Short- and Long-Term Disability Insurance
Employee Assistance Program (EAP), mental health resources, and wellness programs
Family-friendly benefits, including fertility support and maternity resources
Professional development and career growth opportunities within a leading global CRO/CDMO
How to Apply:
Ready to seize this incredible opportunity? Join us at Pharmaron and be part of a dynamic team driving innovation and excellence in biopharmaceutical research and development. Apply online today!
As an Equal Employment Opportunity and Affirmative Action employer, Pharmaron values diversity and inclusion in the workplace, fostering an environment where all individuals are empowered to succeed. Join us in our mission to make a difference in the world of life sciences.
About Pharmaron
Pharmaron (Stock Code: 300759.SZ/3759.HK) is a premier R&D service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities, and established a broad spectrum of research, development and manufacturing service capabilities throughout the entire drug discovery, preclinical and clinical development process across multiple therapeutic modalities, including small molecules, biologics and CGT products. With over 19,000 employees, and operations in China, the U.S., and the U.K., Pharmaron has an excellent track record in the delivery of R&D solutions to its partners in North America, Europe, Japan and China.
Pharmaron is proud to be an Equal Employment Opportunity and Affirmative Action employer.
Salary Range: $200 - $285k (DOE)
Location: Baltimore, MD (On-site)
About Pharmaron
Pharmaron is a global contract research and manufacturing organization (CRO/CDMO) helping pharma and biotech companies bring new therapies to life. With over 25,000 employees worldwide across 28 locations in the US, UK, China, and Singapore, we support drug discovery through to manufacturing with fully integrated high-quality services.
We're proud of the impact we make and just last year, we supported 887 discovery projects, 1,100+ CMC programs, and 1,397 clinical trials across all phases. Our teams are involved in everything from small molecules, ADC's, biologics, and gene therapies and we work with more than 3,300 global customers. To learn more, visit www.pharmaron.com.
What You'll Do
Pharmaron is seeking an experienced physician to serve as a Principal Investigator within our growing Phase I Clinical Research Unit in Baltimore, Maryland.
This is a unique opportunity for a board-certified physician who is passionate about advancing medicine through clinical research while maintaining a strong focus on participant safety and quality care. Clinical research experience is welcomed but not required. Physicians with backgrounds in Internal Medicine, Family Medicine, Emergency Medicine, or related specialties are encouraged to apply.
As Principal Investigator, you will provide medical leadership for early-phase clinical studies, oversee participant safety, collaborate with sponsors and scientific teams, and help shape the future growth of our clinical research programs.
Key Responsibilities:
Clinical Leadership
Serve as Principal Investigator or Sub-Investigator for Phase I-III clinical studies
Provide medical oversight and ensure participant safety throughout study conduct
Review eligibility, medical histories, adverse events, and safety data
Conduct physical examinations and medical assessments as required
Study Execution & Scientific Collaboration
Partner with sponsors and internal teams on protocol review, study design, and implementation
Support dosing activities and ongoing medical monitoring
Contribute to study interpretation, reporting, and regulatory submissions
Provide scientific and medical consultation to project teams and clients
Regulatory & Quality Oversight
Ensure studies are conducted in compliance with ICH-GCP, FDA regulations, and applicable guidelines
Maintain protocol integrity and oversight responsibilities as listed on FDA Form 1572
Support inspections, audits, and regulatory interactions when required
Team Leadership
Mentor and guide Clinical Research Coordinators, nurses, and study staff
Promote a culture of participant safety, quality, and operational excellence
Collaborate closely with Medical, Clinical Operations, Pharmacy, Laboratory, and Business Development teams
What We're Looking For:
Required Qualifications
MD or DO degree from an accredited medical school
Board Certification in a recognized specialty
Active and unrestricted medical license
Minimum 5 years of clinical practice experience
Current CPR and ACLS certifications
Strong understanding of patient care, medical ethics, and clinical decision-making
Excellent communication and leadership skills
Preferred Qualifications
Previous clinical research experience as a Principal Investigator, Sub-Investigator, or treating physician
Experience supporting Phase I or early clinical development programs
Familiarity with ICH-GCP, FDA regulations, and clinical trial operations
DEA registration
Background in Internal Medicine, Family Medicine, or Emergency Medicine
Why Pharmaron?
Pharmaron is a premier service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities and established a broad spectrum of research, development, and manufacturing service capabilities throughout the entire drug discovery, preclinical, and clinical development process across multiple therapeutic modalities, including small molecules, biologics, and CGT products. With over 25,000 employees and operations in the US, UK, China, and Singapore. Pharmaron has an excellent track record in delivering R&D solutions to its partners in North America, Europe, Japan, and China.
Collaborative Culture: You will thrive in our inclusive and collaborative environment, where teamwork and innovation go hand in hand. Here, your voice matters, and your contributions make a real impact. "Employees Number One" and "Clients Centered" are the core cultural values at Pharmaron. Our culture, which sets Pharmaron apart from other organizations, has evolved from our deep commitment to our employees, partners, and collaborators.
Benefits: As part of our commitment to your well-being, we offer a comprehensive benefits package:
Comprehensive Medical, Dental & Vision Insurance with significant employer contributions
401(k) Retirement Plan with generous employer matching
Generous Paid Time Off (PTO), Paid Sick Leave & Company Holidays to support work-life balance
Employer-funded Health Savings Account (HSA) contributions (for eligible plans), plus Healthcare & Dependent Care Flexible Spending Accounts
100% Employer-paid Employee Life Insurance, AD&D, Short- and Long-Term Disability Insurance
Employee Assistance Program (EAP), mental health resources, and wellness programs
Family-friendly benefits, including fertility support and maternity resources
Professional development and career growth opportunities within a leading global CRO/CDMO
How to Apply:
Ready to seize this incredible opportunity? Join us at Pharmaron and be part of a dynamic team driving innovation and excellence in biopharmaceutical research and development. Apply online today!
As an Equal Employment Opportunity and Affirmative Action employer, Pharmaron values diversity and inclusion in the workplace, fostering an environment where all individuals are empowered to succeed. Join us in our mission to make a difference in the world of life sciences.
About Pharmaron
Pharmaron (Stock Code: 300759.SZ/3759.HK) is a premier R&D service provider for the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities, and established a broad spectrum of research, development and manufacturing service capabilities throughout the entire drug discovery, preclinical and clinical development process across multiple therapeutic modalities, including small molecules, biologics and CGT products. With over 19,000 employees, and operations in China, the U.S., and the U.K., Pharmaron has an excellent track record in the delivery of R&D solutions to its partners in North America, Europe, Japan and China.
Pharmaron is proud to be an Equal Employment Opportunity and Affirmative Action employer.
Additional Details
- City
- Baltimore
- State
- Maryland
- Country
- US
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