Principal Clinical Scientist
Alignerr · Raleigh, NC
CONTRACT
Posted Sep 7, 2026
Job Description
Principal Clinical Scientist (AI Training)
About The Role
What if your expertise in clinical trial design and regulatory science could directly shape how AI reasons about clinical evidence — influencing the systems that will power the next generation of biomedical research?
We're looking for a Principal Clinical Scientist to bring senior-level rigor to AI-driven research workflows. You'll work alongside world-leading AI research teams to ensure that clinical data used to train and evaluate advanced AI systems meets the standards expected in real-world regulatory submissions.
This is a fully remote, flexible contract role built for seasoned clinical scientists who want to do meaningful, frontier work — on their own schedule.
- Organization: Alignerr
- Type: Hourly Contract
- Location: Remote
- Commitment: 10–40 hours/week
What You'll Do
- Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training
- Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance
- Evaluate AI-generated clinical analyses for scientific soundness and alignment with FDA, EMA, or equivalent regulatory expectations
- Provide structured expert feedback that directly improves how AI models reason about clinical trial data, endpoints, and outcomes
- Help establish the scientific standards that define how frontier AI understands clinical evidence
Who You Are
- Senior-level clinical scientist with hands-on experience designing trial protocols for regulatory submission
- Deep expertise interpreting clinical data for major regulatory agencies (FDA, EMA, or equivalent)
- Strong grounding in clinical research methodology, biostatistics, translational science, or a related discipline
- Meticulous, detail-oriented, and comfortable working independently with minimal oversight
- Able to translate complex regulatory and clinical concepts into clear, structured written feedback
Nice to Have
- Prior experience with data annotation, data quality evaluation, or AI training workflows
- Background in pharmacovigilance, health technology assessment, or evidence synthesis
- Familiarity with AI tools or clinical decision support systems as an end user
Why Join Us
- Work directly on frontier AI systems making a real impact on clinical and biomedical research
- Fully remote and flexible — work when and where it suits you
- Freelance autonomy with the structure of meaningful, project-based work
- Influence how AI understands, evaluates, and reasons about real-world clinical evidence
- Collaborate with leading AI research teams and labs on cutting-edge projects
- Potential for ongoing work and contract extension as new projects launch
About The Role
What if your expertise in clinical trial design and regulatory science could directly shape how AI reasons about clinical evidence — influencing the systems that will power the next generation of biomedical research?
We're looking for a Principal Clinical Scientist to bring senior-level rigor to AI-driven research workflows. You'll work alongside world-leading AI research teams to ensure that clinical data used to train and evaluate advanced AI systems meets the standards expected in real-world regulatory submissions.
This is a fully remote, flexible contract role built for seasoned clinical scientists who want to do meaningful, frontier work — on their own schedule.
- Organization: Alignerr
- Type: Hourly Contract
- Location: Remote
- Commitment: 10–40 hours/week
What You'll Do
- Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training
- Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance
- Evaluate AI-generated clinical analyses for scientific soundness and alignment with FDA, EMA, or equivalent regulatory expectations
- Provide structured expert feedback that directly improves how AI models reason about clinical trial data, endpoints, and outcomes
- Help establish the scientific standards that define how frontier AI understands clinical evidence
Who You Are
- Senior-level clinical scientist with hands-on experience designing trial protocols for regulatory submission
- Deep expertise interpreting clinical data for major regulatory agencies (FDA, EMA, or equivalent)
- Strong grounding in clinical research methodology, biostatistics, translational science, or a related discipline
- Meticulous, detail-oriented, and comfortable working independently with minimal oversight
- Able to translate complex regulatory and clinical concepts into clear, structured written feedback
Nice to Have
- Prior experience with data annotation, data quality evaluation, or AI training workflows
- Background in pharmacovigilance, health technology assessment, or evidence synthesis
- Familiarity with AI tools or clinical decision support systems as an end user
Why Join Us
- Work directly on frontier AI systems making a real impact on clinical and biomedical research
- Fully remote and flexible — work when and where it suits you
- Freelance autonomy with the structure of meaningful, project-based work
- Influence how AI understands, evaluates, and reasons about real-world clinical evidence
- Collaborate with leading AI research teams and labs on cutting-edge projects
- Potential for ongoing work and contract extension as new projects launch
Additional Details
- City
- Raleigh
- State
- North Carolina
- Country
- US
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