Principal Clinical Scientist

**Principal Clinical Scientist (AI Training)** **About The Role** What if your expertise in clinical trial design and regulatory-grade data interpretation could directly shape how AI reasons about biomedical evidence --- influencing systems used by researchers and clinicians worldwide?

We're looking for a Principal Clinical Scientist to bring senior-level rigor to AI-driven research workflows. You'll work with cutting-edge AI teams to ensure clinical data used in training and evaluation meets the standards expected in real-world regulatory submissions.

This is a fully remote, flexible contract role built for experienced clinical scientists who want to do meaningful work --- on their own schedule.

* Organization: Alignerr
* Type: Hourly Contract
* Location: Remote
* Commitment: 10--40 hours/week

**What You'll Do**

* Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training
* Interpret and audit clinical trial results for accuracy, consistency, and regulatory relevance
* Evaluate AI-generated clinical analyses for scientific soundness and alignment with FDA, EMA, or equivalent regulatory expectations
* Provide structured expert feedback that helps AI models reason more accurately about clinical trial data, outcomes, and evidence
* Flag methodological gaps, ambiguities, or misrepresentations in AI-generated clinical content

**Who You Are**

* Senior-level professional with deep experience designing clinical trial protocols for regulatory submission
* Highly skilled at interpreting clinical data for regulatory agencies such as the FDA, EMA, or equivalent bodies
* Strong grounding in clinical research methodology, biostatistics, or translational science
* Detail-oriented and systematic --- you hold clinical data to the highest standards of rigor
* Comfortable working independently and asynchronously in a remote, task-based environment

**Nice to Have**

* Prior experience with data annotation, data quality evaluation, or AI content review
* Familiarity with AI tools or language model outputs in a scientific context
* Background in biomedical informatics, health technology assessment, or evidence synthesis

**Why Join Us**

* Work directly on frontier AI systems making an impact in clinical and biomedical research
* Influence how AI understands, evaluates, and communicates real-world clinical evidence
* Fully remote and flexible --- work when and where it suits you
* Freelance autonomy with the structure of meaningful, expert-level work
* Collaborate with leading AI research teams and labs at the cutting edge of the field
* Potential for ongoing work and contract extension as new projects launch