Principal Clinical Data Manager
Worldwide Clinical Trials · Wilmington, DE
FULL-TIME
Posted Nov 14, 2026
99K–196K a year
Job Description
Where You'll Work
This is a REMOTE role open to candidates based in US. You will collaborate with global teams across multiple time zones.
What You'll Do
• Lead end-to-end clinical data management activities across multiple complex global projects and programs.
• Ensure data management deliverables, timelines, budgets, and resources are effectively planned and managed.
• Oversee the development and review of key study documentation, including Data Management Plans, database specifications, edit checks, and data transfer agreements.
• Direct user acceptance testing, data cleaning strategies, reconciliation activities, and database lock readiness to ensure high-quality study data.
• Monitor study progress through metrics and proactively identify, communicate, and mitigate project risks and scope changes.
• Serve as the primary data management representative in internal and sponsor-facing meetings, providing expert guidance and leadership.
• Act as a subject matter expert for designated data management processes, driving process optimization, training, quality improvement, and CAPA activities.
• Mentor and support data management colleagues while contributing to departmental initiatives and operational excellence programs.
• Support business development activities, sponsor audits, inspections, and other key stakeholder engagements as needed.
What You'll Bring
• Bachelor's degree or higher in biomedical sciences, life sciences, computer science, or a related field, or equivalent relevant experience.
• Minimum 7 years of clinical data management experience or related experience within the pharmaceutical, biotechnology, or medical device industries.
• Expert knowledge of clinical data management best practices, technologies, and processes supporting clinical trials.
• Advanced understanding of clinical trial documentation and processes, including protocols, CRFs, statistical analysis plans, and study reports.
• Proven ability to independently lead and oversee complex global clinical data management projects.
• Strong analytical, problem-solving, and decision-making skills with exceptional attention to detail.
• Excellent communication and interpersonal skills with the ability to collaborate effectively across internal and external stakeholder groups.
• Proficiency in English.
At Worldwide Clinical Trials, we are committed to fostering an inclusive and equitable workplace by providing transparent compensation.
The salary range for this position is annually (For hourly paid positions, the stated salary range reflects hourly rates):
United States of America - $99,000.00 - $196,000.00
The salary range provided is intended to give candidates an understanding of potential earnings. Compensation will fall within the provided range, and it not a guarantee of exact salary. The final salary will be determined based on relevant experience, performance, education, and internal equity. In addition to base salary, we offer a competitive benefits package depending on location. We ensure pay equity and transparency and comply with all applicable labor laws. Salary information will be discussed during the interview process, and we encourage candidates to inquire about compensation at any stage.
This is a REMOTE role open to candidates based in US. You will collaborate with global teams across multiple time zones.
What You'll Do
• Lead end-to-end clinical data management activities across multiple complex global projects and programs.
• Ensure data management deliverables, timelines, budgets, and resources are effectively planned and managed.
• Oversee the development and review of key study documentation, including Data Management Plans, database specifications, edit checks, and data transfer agreements.
• Direct user acceptance testing, data cleaning strategies, reconciliation activities, and database lock readiness to ensure high-quality study data.
• Monitor study progress through metrics and proactively identify, communicate, and mitigate project risks and scope changes.
• Serve as the primary data management representative in internal and sponsor-facing meetings, providing expert guidance and leadership.
• Act as a subject matter expert for designated data management processes, driving process optimization, training, quality improvement, and CAPA activities.
• Mentor and support data management colleagues while contributing to departmental initiatives and operational excellence programs.
• Support business development activities, sponsor audits, inspections, and other key stakeholder engagements as needed.
What You'll Bring
• Bachelor's degree or higher in biomedical sciences, life sciences, computer science, or a related field, or equivalent relevant experience.
• Minimum 7 years of clinical data management experience or related experience within the pharmaceutical, biotechnology, or medical device industries.
• Expert knowledge of clinical data management best practices, technologies, and processes supporting clinical trials.
• Advanced understanding of clinical trial documentation and processes, including protocols, CRFs, statistical analysis plans, and study reports.
• Proven ability to independently lead and oversee complex global clinical data management projects.
• Strong analytical, problem-solving, and decision-making skills with exceptional attention to detail.
• Excellent communication and interpersonal skills with the ability to collaborate effectively across internal and external stakeholder groups.
• Proficiency in English.
At Worldwide Clinical Trials, we are committed to fostering an inclusive and equitable workplace by providing transparent compensation.
The salary range for this position is annually (For hourly paid positions, the stated salary range reflects hourly rates):
United States of America - $99,000.00 - $196,000.00
The salary range provided is intended to give candidates an understanding of potential earnings. Compensation will fall within the provided range, and it not a guarantee of exact salary. The final salary will be determined based on relevant experience, performance, education, and internal equity. In addition to base salary, we offer a competitive benefits package depending on location. We ensure pay equity and transparency and comply with all applicable labor laws. Salary information will be discussed during the interview process, and we encourage candidates to inquire about compensation at any stage.
Additional Details
- City
- Wilmington
- State
- Delaware
- Country
- US
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