Clinical Research Principal Investigator (MD, DO) - Flexible Schedule
Physician Pivot · Rock Hill, SC
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FULL-TIME
Posted Oct 14, 2026
Job Description
Job Summary
We are seeking a highly motivated and experienced Clinical Research Principal Investigator (MD, DO) to lead and oversee clinical research projects within a dynamic research environment. This role offers a flexible schedule, allowing for a balanced approach to research leadership and patient care. As the Principal Investigator (PI) is responsible for the overall conduct and medical oversight of clinical trials, ensuring participant safety, protocol compliance, regulatory adherence, and the integrity of study data.
Responsibilities
• Serve as the Principal Investigator for assigned clinical research studies.
• Provide medical oversight and ensure participant safety throughout study participation.
• Evaluate and determine participant eligibility.
• Review study-related medical documentation, adverse events, and protocol deviations.
• Ensure compliance with FDA regulations, ICH-GCP guidelines, and sponsor requirements.
• Collaborate with sponsors, CROs, monitors, and research staff.
• Participate in investigator meetings, monitoring visits, and study audits.
• Support patient recruitment and retention efforts.
• Review and sign study-related documentation as required.
Requirements
• Active, unrestricted MD or DO license.
• Board Certified or Board Eligible.
• Strong clinical judgment and patient care experience.
• Excellent communication and leadership skills.
LightDay Clinical Trials is committed to advancing healthcare through ethical, high-quality clinical research. Our mission is to improve access to innovative treatment options while delivering exceptional care and research opportunities to our community.
Pay: $100.00 - $200.00 per hour
Expected hours: 1.0 – 4.0 per week
Work Location: Hybrid remote in Rock Hill, SC 29730
We are seeking a highly motivated and experienced Clinical Research Principal Investigator (MD, DO) to lead and oversee clinical research projects within a dynamic research environment. This role offers a flexible schedule, allowing for a balanced approach to research leadership and patient care. As the Principal Investigator (PI) is responsible for the overall conduct and medical oversight of clinical trials, ensuring participant safety, protocol compliance, regulatory adherence, and the integrity of study data.
Responsibilities
• Serve as the Principal Investigator for assigned clinical research studies.
• Provide medical oversight and ensure participant safety throughout study participation.
• Evaluate and determine participant eligibility.
• Review study-related medical documentation, adverse events, and protocol deviations.
• Ensure compliance with FDA regulations, ICH-GCP guidelines, and sponsor requirements.
• Collaborate with sponsors, CROs, monitors, and research staff.
• Participate in investigator meetings, monitoring visits, and study audits.
• Support patient recruitment and retention efforts.
• Review and sign study-related documentation as required.
Requirements
• Active, unrestricted MD or DO license.
• Board Certified or Board Eligible.
• Strong clinical judgment and patient care experience.
• Excellent communication and leadership skills.
LightDay Clinical Trials is committed to advancing healthcare through ethical, high-quality clinical research. Our mission is to improve access to innovative treatment options while delivering exceptional care and research opportunities to our community.
Pay: $100.00 - $200.00 per hour
Expected hours: 1.0 – 4.0 per week
Work Location: Hybrid remote in Rock Hill, SC 29730
Additional Details
- City
- Rock Hill
- State
- South Carolina
- Country
- US
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