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Droplet Biosciences, Inc logo

Clinical Lab Technologist III

Droplet Biosciences, Inc · Cambridge, MA

FULL-TIME Posted Nov 14, 2026

Job Description

Droplet Biosciences is seeking a Clinical Lab Technologist III to run laboratory operations and clinical testing in our CLIA/CAP laboratory. As the core member of the clinical testing team, this individual will be integral to the success and expansion of the CLIA lab towards Droplet’s mission of transforming precision oncology.
Responsibilities:
Act as key testing personnel for our MRD diagnostic test LymphDetect, ensuring the highest quality of patient care while meeting regulatory and compliance standards.
Oversee and manage daily laboratory operations.
Implement and enforce all Standard Operating Procedures (SOPs) and Personal Protective Equipment (PPE) protocols.
Serve as the laboratory safety lead, ensuring compliance with Environmental Health & Safety (EH&S) requirements, including chemical hygiene, biohazard handling, incident reporting, and safety training.
Supervise, mentor, and train clinical laboratory staff, conducting performance reviews and competency assessments.
Provide consultation to resolve technical problems in accordance with policies and procedures.
Conduct basic data analysis to monitor lab operation and performance.
Ensure that acceptable levels of analytical performance are maintained on a day to day basis.
Collaborate with other departments, including clinical development, assay development, and quality assurance.
Participate in new method and procedure change validations and documentation.
Stay current with the latest trends in liquid biopsy and next generation sequencing methods and testing, sharing knowledge with Droplet Biosciences leadership and staff
Oversee tech transfer and contribute to other company goals as needed.
Qualifications:
Bachelor’s degree in a chemical, biological, Clinical or Medical Laboratory science from an accredited university.
At least 4 year experience in a high complexity clinical testing laboratory.
Experience with manual next-generation sequencing library construction methods (Whole genome or hybrid capture).
Expertise with basic molecular biology techniques as well as nucleic acid extraction and quality control techniques.
Are mission-driven, humble and wants to connect contributions to the big picture.
Desired Qualifications:
3+ years next generation sequencing experience
Previous experience in liquid biopsy or cancer diagnostic field.
Compensation and benefits
Compensation will be commensurate with experience and competitive on both salary and equity. We offer generous health benefits and a 401k plan.
About Droplet Biosciences:
Founded in 2021, Cambridge, MA-based Droplet Biosciences provides earlier and more sensitive cancer diagnostics by harnessing the power of lymphatic fluid. Droplet’s approach uses next-generation sequencing to offer non-invasive detection of circulating tumor DNA at the landmark time point when adjuvant treatment decisions are most critical. For more information, visit http://www.dropletbiosci.com/.
If you are looking to apply your expertise in high complexity testing to bring innovative diagnostics to cancer patients, please apply.

Additional Details

City
Cambridge
State
Massachusetts
Country
US
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